Investigational Product/ Process /Intervention
Research Description/ Research Lay Summary
This is a multi-center, prospective study which will register all patients with nasopharyngeal carcinoma whom fit the inclusion criteria from those that are referred to the participating centers from 2007 – 2009. All cases will be followed up for 3 years. Further funding will be required upon completion of the initial registry for on-going data updates and maintenance.
Research Keyword
Nasopharyngeal carcinoma, clinical outcome, NPC database, NPC tissue bank, Cancer treatment outcome
Research Objective
1) To establish a national NPC clinical database:
- to describe the crude and relative survival of NPC patients
- to determine the perdictors of poor survival
- to determine the post treatment morbidity rates in terms of recurrence (both local and distant failures)
- to determine the side effects (toxicity) experienced by NPC patients undergoing radiotherapy and/or chemotherapy
- to identify predictors of post treatment complications (morbidity)
2) To establish a national NPC tissue bank:
- to enable the identification, validation and characterisation of new biomarkers, including markers for disease detection, classification, prognosis and therapy
Expected / Actual Date Study Starts - First Enrolment of subject / Collecting data
Jan, 01 2007
Expected / Actual Date Study Completed
Dec, 31 2009
Expected / Actual Duration of Study Enrollment / Data Collection
156 weeks
Subject (Sample Size) Description
Age Range :
Gender :
Biospecimen Collection & Archiving
-
Current Study Status
Recruiting
Principal Investigator Information
Dr Pua Kin Choo
Pulau Pinang Hospital
Sponsor
Ministry of Health
Ethical Application Status
Individual Clinical Trial Participant–level Data of Individual Participant Data (IPD) Sharing